Have been isolated
score of alkaloids of the type of piperidine and methylpiperidine, the most important of which is lobeline. They also highlight the lobelanina and lobelanidina.
adrenergic (sympathomimetic) increases the frequency and strength of the
, serving as coronariodilatadora, decreases peristalsis and increases
glycogen, inhibit bile secretion, decreased urine output, is vasoconstrictor, it increases blood pressure. By unloading produce adrenaline, stimulates the
- level centers bulbares, producing bronchodilation. The isolobinina
balmy, expectorant and antiasmático.
(such as emergency medication) For his gangliopléjico effect similar to nicotine (it acts as an antagonist) advocated their use in nicotine
, lactation. Do not prescribe psychiatric drugs simultaneously or with other drugs alkaloids.
Caution / Poisoning.
very toxic plant (DL = 4g) can cause vomiting,
, hypotension, tachycardia, and bradycardia, followed by anxiety, stupor, convulsions and death from
Due to differences in the composition of the plant depending on its provenance, it is more advisable to use standardized forms, valued at lobeline, or alkaloids isolated or semisynthetic.
Galenica forms / Dosage.
10) 100 - 300 mg, one to three times
day. Maximum dose = 3 g / day.
50 to 300 grams, one to three times
day. Maximum dose = 1. 5 g / day.
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