, alexanderbain; al. Klatsch - Mohn;
This annual plant with leaves and hairs cut very dimeric whose flowers have
, they have
black mark on the base. The species,
and southern Europe, grows abundantly along the roads in places uneducated.
color of the petals is due to the presence of anthocyanins (soforosil - 3 cianidol) The alkaloids present in the plant - derived from tetrahydro - 3 -
- benzoazepina - are also found in the petals: roeadina, the main component, is accompanied by at least three other alkaloids. The total alkaloid content is close to 0. 07%.
It is not known very well the pharmacology of roeadina and their counterparts. Of the
not been studied,
consumption of some preparations produces effects similar to those caused by benzodiazepines. On the other hand, are known to the
- 1 tetrahydro - 3 -
- 3 - benzoacepinas and their counterparts are neuroleptics and antagonists at the level of dopamine receptors.
In addition to being part of "pectoral species", the
is regarded as
sedative and antitusiva, being advised in
of sleep and
in the exaltation of palpitations. The LD50 of roeadina is 530 mg / kg (rat, ip) The drug spray administered to rats by mouth, does not disclose clinical trials of acute and subacute. In Spain authorizing the use of this plant for the treatment of
, anxiety, emotion.
Because of anthocyanins may appear stool
. Warn the patient.
The petals are ovoid, with the edges and fine whole. Once dried, are colored
Teedrogen - Ein Handbuch fur die praxis auf Grundlage Wissenschaftlicher, M. Wicht, ed. 2nd ed. Stuttgart, Wissenschaftliche Verlagsgesellshaft mbH,
. 276 - 277, 1988.
Rhoeadine alkaloids. In:
The alkaloids, chemistry and pharmacology,
. BROSSI, ed. Orlando, Academic Press, vol. 28,
. 1 - 94, 1986.
b) Y. N. KALAV G. et SARIYAR.
Alkaloids from turkish Papaver rhoeas.
. 55, 488, 1989.
. S. ABBE et
Identification dosage et du groupe des alkaloids from the rhoeadine pair HPLC - UV in Papaver rhoeas L.
Communication par affiche, VIème
Symposium dedicated aux medicinal plants and aux Substances Naturelles, 3 - 4 juin 1988, Angers (France)
Elles ont plants invented them azepin avant nous?
Medisearch, No. 17, 37 - 41, 1987.
. ALI, W.
. BONDINELL, M. BRENNER,
. G. HOLDEN,
. W. KU,
. J. OH, S.
. ROSS, N.
. L. ZIRKLE, R.
. M. SARAU,
. SETL et J. R. Wardell.
6 - phenylthio) substituted 2, 3, 4, 5 - tetrahydro - 1,
- 3 - benzazepines,
novel class of dopamine receptor antagonists and neuroleptics. J. Med. Chem. 23, 975 - 976, 1980.
coquelicot, toxicologique dossier. Travaux des Laboratoires
whose treatment is appropriate in this plant.