He is most serious of the
dystrophies and is caused by the absence in the
Its cause is
and it must to the lack or mutation of
gene in the chromosome X that
and that is in
to issue the
cells to produce the distrofina
, that normally is inside the membrane that surrounds
fiber and whose
is to cause that they work suitably.
Normally, the damaged fibers are replaced by cellular regeneration during the first years of the
limit and the
surpasses the conditions of regeneration.
It affects the men who generally inherit the gene of their
and can initiate between the 2 and 6 years of age and their incidence it is of one between
5. 000 born
. The inheritance of the damaged gene nevertheless comes from the father who inherits to some of his daughters or
This hereditary process is
been identified that:
Only the women are carrying of the damaged gene and can inherit it to the
Only the affected men, can inherit it to their daughters.
Only the men present / display the symptoms of the
, and are very rare the women who present / display them.
the probabilities that
son affected man or
carrying daughter, is of 50% percent.
30% percent of the cases, the
are not inherited by the
who must to
mutation of the gene in the affected man.
the men sometimes who inherit gene of their mothers and affects progressive, slowly and per periods he advances quickly, mainly the torso and the muscles of the extremities, reason why to short age, the
must use wheelchair to be transported.
The gravity of this
is in which the pectoral muscles are debilitated of such form which they produce
insufficiency or pulmonÝa burdens, which generally and between the 20 and 30 years, takes them to the death.
The advance of the
is different in
boy, with the help of ortopÚdicos apparatuses and therapy can walk
little more, nevertheless the average to let do it and to use wheelchair is of 12 years.
The content of this note is informative and it does not replace the medical diagnosis, reason why we do not become people in
on its use.