It is the most
Closely related to age, appears in the autopsies of more than 40% of men of fifty years, to increase its frecuensia to 67% (one in three) between 80 and 89 years.
Nevertheless, the appearance of symptoms of the same in life is much lower (about one per cent)
The risk of developing
Spanish 50 - year lifetime is about 40%,
this clinical symptoms that occur less than 10%, and the possibility that it produces is below the muetre 3%.
It depends on the evolutionary stage where it
can be cured without affectation of hope or quality of life.
The hormone reduces the quality of life, to cancel
can be cured locally advanced,
more often falling in less than three years, reducing life expectancy.
reduces life expectancy, although initially usually stop with treatment.
The basic cause is unknown, although various theories and data pointing to
Signs and symptoms.
Initially produce few symptoms.
The presence of
Delay in starting urination,
Jet recently Urine powerful, with breaks,
Dribbling after finishing.
is much more
Already very advanced cancers cause:
in his legs, with swelling,
Bone pain, especially
neurological symptoms (
, lack of emptying of the
with retention of urine)
It is assumed that there are environmental or dietary factors that influence their progress,
have not yet been able to realize.
obstruction, with impact on the kidneys.
column, for metastasis.
Neurological effects caused by the above.
Diagnosis and Treatment.
The usual procedure for diagnosis comes as follows:
rectal screening in asymptomatic people.
In cases in which the gland is enlarged and hardened, is
determination of tumor markers in the blood (PSA)
Its outcome should be interpreted with great caution in this context, since this test produces many false positives (say that
healthy person is sick) and negative (say
patient is healthy) so they're much more useful for monitoring the
that his initial diagnosis. It also explores other parameters in the blood, more indicative of distance
It is desirable, if there is
symptoms, studies of renal
Then, to confirm or ensure the diagnosis is proceeded to
puncture biopsy transrectal (obtaining
tissue sample through the introduction of
needle from the rectum is
From here, is passed to the visualization techniques, to assess the chances surgery (before doing so produces confusing results)
Ultrasonography: Allows you to detect if the
is confined to the
overflowed. Also used to guide the needle into the pre - puncture biopsy.
Nuclear Magnetic Resonance (NMR) Allows you to evaluate the pelvic lymph nodes (which will soon affect, and whose involvement influences the therapeutic decision)
. CT, scanner) Used recently passed by the RMN.
It is used to detect bone metastases.
Once you've made all these tests, determining the degree of volution of the tumor and the most appropriate therapeutic intervention.
Treatment of localized
There are three possibilities:
Surgical removal of the gland. Very effective in selected patients, usually the preserve
) in most patients, and
in selected cases.
Radiotherapy. Effective alternative in selected cases, it avoids the need for intervention. Well implemented, facilitate the preservation of
In some selected cases, may be the best option,
treatment for any of the above methods prolongs survival in general, it is not the first option.
Treatment of locally advanced
In these cases the
treatment is being intensively investigated.
Combining the techniques of previous techniques with hormone treatment:
By relying on
tissue of male hormones, its cancellation caused its demise, at least in part.
Today the agents of choice are the LHRH antagonist (Leuprolida, etc. So effective that avoid the need for surgical castration (previously required to avoid
of male hormones) or other similar measures.
often accompany, so that
complete blockade of androgenic receptor antagonists (flutamide, etc.
Produce cancellation of
Treatment of metastatic
In these cases, treatment is limited to the hormonal patterns.
For some bone metastases causing symptoms,
therapy can be applied locally.
They are very important palliative care (treatment of pain,
, bone lesions,